EIMERIX®

(powder for oral administration)

Description

Loose granular powder of grey-brown colour, without impurities, with a faint specific odor.

Composition

100 g of the drug contains:

active ingredient: sodium monensin – 20 g;

Excipient: calcium carbonate.

Pharmacological properties

АТС vet QP51 - antiprotozoals. QP51АН03 — monensin.

Eimerix® is an antiprotozoal, containing sodium monensin (20%) of ionophore action as an active ingredient and excipients. It is effective against Eimeria tenella, E. acervulina, E. mivati, E. brunetti, E. necatrix, E. maxima, E. adenoeides, E. meleagrimitis, E. gallopavonis in chickens and turkeys. Monensin interrupts transport of monovalent ions of potassium and sodium in cells of the mentioned coccidia, resulting in their swelling and vacuolization. Monensin molecules increase intracellular sodium concentration. The parasite dies due to osmotic pressure disruption. Monensin acts upon eimeria in the states of sporozoites and trophozoites.

Sodium monensin is ingested in chicken bodies and forms dimethyl oxidative and decarboxylized metabolites, present in feces and tissues, where the contents of either metabolite does not exceed 10% of total number of compounds. Monensin residue test in chickens and turkeys after administration demonstrated that the drug level was the highest in skin, fat and liver.

Sodium monensin is rapidly excreted in bile.

Administration

Prevention and treatment of eimeriosis in hens (broiler chickens), caused by Eimeria: Еimeria necatrix, Е. tenella, E. acervulina, Е. maxima, Е. mivati, Е. brunetti.

Prevention and treatment of eimeriosis in tukeys (under 16 weeks old), caused by Eimeria: Еimeria adenoeides, Е. gallopavonis, Е. meleagrimitis.

Dosage

Eimerix® is administered with feed in the following doses:

broiler chickens, pullets: 500‒625 g of the drug per 1 t of feed (equivalent to 100.0‒125.0 g of monensin sodium per 1 t of feed); broiler chickens are fed with feed throughout the fattening period from one day old and the drug is excluded from the diet for 5 days before slaughter, pullets are used from one day of age for 15-16 weeks.

Turkeys (under 16 weeks old): 450‒500 g of the drug per 1 t of feed (equivalent to 90.0‒100.0 g of monensin sodium per 1 t of feed), is used throughout the growing period up to 16 weeks old.

To provide uniform distribution, the daily dose of Eimerix® is mixed with a small amount of feed, and then, mixing thoroughly, make it into the daily feed ration.

Contraindications

Do not prescribe to laying hens and other adult poultries (particularly, waterfowl)!

It is strictly forbidden to administer to horses and other odd-toed animals!

Precautions

Slaughter of broiler chickens and turkeys for meat is allowed in 5 days following the last drug administration.

Sodium monensin is incompatible with certain drugs, particularly – with tiamulin. Therefore, tiamulin-containing products may be administered to broiler chickens, pullets of egg crosses and turkeys in 7 days to and 7 days after Eimerix® administration.  If these drugs are combined, severe complications and death of poultry is possible.

When using the drug, observe principal hygiene and safety requirements adopted for work with veterinary drugs, avoid drug inhalation and contact with open skin areas.  In case of incidental contact with eyes rinse them immediately with running water.

Packaging

Polyethylene bags of 25 kg packed in paper bags.

Storage

Store in original air tight packaging in a dry and well-ventilated place protected from direct sunlight at 0-30 °C.

Shelf life

2 years.

3 months after mixing with feed.

For veterinary use only!