MADURO® FORTE

powder for oral administration

Description

Light-brown powder.

Composition

1 g of the drug contains:

active ingredients: maduramicin ammonium - 9 mg; diclazuril – 2 mg;

excipient: wheat groats.

Pharmacological properties

ATC vet QP51 - antiprotozoals. QP51AX10 - maduramicin, QP51AJ03 - diclazuril.

Properties of Maduro® Forte are conditioned by the result of combination of active ingredients: maduramicin ammonium and diclazuril.

Maduramicin is an eimeriostatic of the ionophore group. It is active against eimeria (Eimeria tenella, E.  acervulina, E. necatrix, E. mivati, E. maxima, E. brunetti)) at the stages of sporozoites, trophozoites and schizoids of the first generation. The mechanism of drug action is to disrupt the transport of Na + and K + monovalent ions across the parasite cell membrane its subsequent death.

Diclazuril is an eimeriostatic of the ionophore group. It acts against poultry eimeria(Eimeria acervulina, Е. brunetti, Е. maxima, Е. mitis, Е. necatrix, Е. tenella, Е. adenoeides, Е. gallopavonis, Е. meleagrimitis і т. ін.), rabbits (Е. flavescens, Е. intestinalis, Е. magna, Е. perforans, Е. stiedaе, etc.), cattle, sheep, goats and swine, it disrupts the energy metabolism of endogenous development of eimeria. Asexual forms of endogenic cycle of coccidia development are the most sensitive to the drug.

Administration

Treatment and prevention of coccidiosis caused by various types of eimeria in hens (broiler chickens, pullets up to 16 weeks old) and in turkeys up to 12 weeks old.

Dosage

The drug is fed to poultry with feed in a dose of 500 g of the drug per 1 t of feed (0.5 g of the drug per 1 kg of feed).

Maduro® Forte is thoroughly mixed with feed: first - with a small amount of feed (3-10 % of the total), and then the resulting mixture is mixed with the rest of the feed.

Contraindications

Hypersensitivity to maduramicin and diclazuril. Do not administer to laying hens. Do not prescribe in combination with other anticoccidial drugs. It is forbidden to feed Maduro® Forte for 7 days before, during and for 7 days after tiamulin administration.

Precautions

Non-uniform drug mixing with feed, uneven consumption of medicated feed (hungry, ill animals) as well as excess of recommended drug concentrations in feed may in certain cases result in decrease in animal productivity and even in presence of clinical intoxication signs.

Poultry slaughter for meat is possible in 5 days following the last administration of the drug.

Packaging

Paper or combined packages of 1 kg, bags of 25 kg.

Storage

Store in original packaging in a dry, dark place out of the reach of children and animals at 0-30 °C.

Shelf life

1 year.

For veterinary use only!