NICAMAX®

powder for oral administration

Description

Yellow powder.

Composition

1 kg of the drug contains:

active ingredients: maduramycin ammonium - 7.5 g; nicarbazin - 80 g;

excipient - corn fibre.

Pharmacological properties

ATC vet QP51 - antiprotozoals. QP51AX30 — combinations of other antiprotozoals.

The drug antiprotozoal effect is due to the synergism of active substances - maduramycin ammonium (ionophore antibiotic) and nicarbazin (dinitrocarbanilide derivative), their low concentrations of which provide effective antiemerious action. Use of Nicamax® is more effective than use of maduramycin ammonium and nicarbazin alone.

Maduramycin is an eimeriostatic group of iontophores, active against eimeria (Eimeria tenella, E acervulina, E. necatrix, E. mivati, E. maxima, E. brunetti)) at the stages of sporozoites, trophozoites and schizoids of the first generation. The mechanism of drug action is to disrupt the transport of Na + and K + monovalent ions across the parasite cell membrane its subsequent death.

Nicarbazin is a synthetic agent, a complex of 4,4'-dinitrodiphenylurea (DNC) and 2-hydro-4,6-dimethylpyrimidine (HDP), inhibiting energy metabolism in the parasite body.

Administration

Prevention and treatment of broiler chickens with eimeriosis caused by eimeria: Е. tenella, E. acervulina, Е. maxima,Е. necatrix, Е. mivati and Е. brunetti.

Dosage

Nicamax® drug is administered to broiler chickens with feed at a dose of 0.5 kg per 1 t of feed from the first day of life during the rearing period, excluding from the diet 5 days before slaughter.

To ensure uniform distribution, the drug daily dose is thoroughly mixed with a small amount of feed (3-10%), and then added with thorough mixing in the feed, used for consumption by poultry during the day.

Contraindications

Do not administer to adult and laying poultry. Do not use in combination with other eimeriostatics. Do not use the drug for 7 days before and 7 days after tiamulin administration.

Precautions

Poultry slaughter for meat is possible in 5 days following the last administration of the drug. Meat, obtained before the mentioned term shall be utilized or fed to non-productive animals depending on the statement of a veterinary physician.

Packaging

Multilayer paper bags or plastic film bags of 1 and 25 kg.

Storage

Store in a dark place out of the reach of children at 5-30 °С.

Shelf life

2 years.

3 months after mixing with feed.

For veterinary use only!